Leszek Kaczmarek is a professor and head of the Laboratory of Neurobiology at the Nencki Institute, Warsaw; Poland. His research aims at understanding the brain-mind connection. He believes that it is possible to localize specific mind functions into the brain and then reveal their molecular and cellular underpinnings. The window to understand mind is learning and memory that can be successfully studied in experimental animals. At the molecular and cellular levels, phenomenon named synaptic plasticity appears to provide plausible explanation for those phenomena. Over the last 30 years his lab identified a synaptic molecule that is produced and released in response to enhanced neuronal activity to play a paramount role in the synaptic plasticity, learning and memory as well as in such neuropsychiatric disorders in humans as epilepsy, alcohol addiction, schizophrenia and bipolar disorder.